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Increase or decrease in appetite
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changes in eating habits
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unexplained weight loss or gain
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Smell of substance on breath, body or clothes
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Extreme hyperactivity
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Excessive talkativeness
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Needle marks or bruises on lower arm, legs or bottom of feet
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Change in overall attitude / personality with no other identifiable
cause
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Changes in friends: new hang-outs, avoidance of old crowd, new friends are drug users
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Change in activities; loss of interest in things that were important before
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Drop in school or work performance; skips or is late to school or work
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Changes in habits at home; loss of interest in family and family activities
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Difficulty in paying attention; forgetfulness
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Lack of motivation, energy, self-esteem, discipline. Bored, "I don't care" attitude
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Defensiveness, temper tantrums, resentful behavior (everything's a hassle)
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Unexplained moodiness, irritability, or nervousness
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Violent temper or bizarre behavior
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Unexplained silliness or giddiness
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Paranoia -- suspiciousness
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Excessive need for privacy; keeps door locked or closed, won't let people in
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Secretive or suspicious behavior
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Car accidents, fender benders, household accidents
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Chronic dishonesty; trouble with police
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Unexplained need for money; can't explain where money goes; stealing
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Unusual effort to cover arms, legs. Change in personal grooming habits
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Possession of drug paraphernalia
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The above are the main signs of addiction but not the only ones. Those signs are a guideline